Researchers have captured the first detailed molecular snapshots of human polynucleotide phosphorylase (hPNPase) in action, ...

This article explores how challenges such as sequence optimization, immune activation and off-target effects are being ...

RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function ...

Researchers have used cryo-EM and computational tools to visualize ribozyme assembly, shedding light on life's most versatile ...

Studying a trio of non-coding RNA molecules produced abundantly in bacterial cells, a SLAC/Stanford-led research team discovered extravagant, multistrand complexes made entirely of RNA—structures they ...

Scientists at the University of Nottingham have developed a technique to analyze the atomic-level structure of RNA molecules with exceptional precision and speed, and are the first in the world to use ...

Just as AlphaFold2's solution to the protein folding problem heralded a new era in biology and contributed to a Nobel Prize, the accurate prediction of RNA structure is widely considered the next ...

The chemical structure of uracil, showing its single-ring pyrimidine structure. Uracil forms hydrogen bonds with adenine in RNA, contributing to the molecule's structure and function. (Image: Public ...

Preclinical in vivo data demonstrate hyper-precise mechanism directly targets the disease-causing mRNA repeats leading to correction of splicing ...

The discovery of a juvenile woolly mammoth named Yuka, found in Siberian permafrost with its skin and muscles intact, has already marked paleontological history. A team of scientists has just ...