eLife

Advantageous and disadvantageous inequality aversion can be taught through learning of others’ preferences

Like disadvantageous inequity aversion, advantageous inequity aversion can be learned by observing another’s fairness preferences.
eLife

Experience-Dependent Plasticity: The little brain supervises learning in the big brain

The cerebellum (which is Latin for ‘little brain’) is the area of the brain in charge of fine motor coordination and balance, and it keeps our movements smooth and stable by predicting what our next ...
eLife

A single-cell transcriptomic atlas reveals resident dendritic-like cells in the zebrafish brain parenchyma

The zebrafish brain combines a conserved heterogeneity of immune cells with a unique dendritic cell-like population.
eLife

Multiscale dynamical characterization of cortical brain states: from synchrony to asynchrony

We conclude that brain states are shaped by local circuit mechanisms, large-scale connectivity and neuromodulation. A unified multiscale theory of cortical dynamics is relevant not only for ...
eLife

State-dependent brain responsiveness, from local circuits to the whole brain

This correspondence between brain state and brain responsiveness (statedependent responses) is outlined at different scales from the cellular and circuit level, to the mesoscale and macroscale level.
eLife

Continuous flashing suppression of V1 responses and the perceptual consequences revealed via two-photon calcium imaging and transformer modeling

Two-photon imaging and ocular dominance mapping. A. Optical windows for imaging of two macaques. Green crosses indicate the regions for viral vector injections, and yell ...
eLife

Deep learning reveals endogenous sterols as allosteric modulators of the GPCR–Gα interface

An AI-driven computational toolkit, Gcoupler, integrates ligand design, statistical modeling, and graph neural networks to predict endogenous metabolites that allosterically modulate the GPCR–Gα ...
eLife

The Fd4 transcription factor translates transient spatial cues in progenitors into long-term lineage identity

Institute of Neuroscience, Howard Hughes Medical Institute, University of Oregon, Eugene, United States ...
eLife

Frequency-selective contrast sensitivity modulation driven by fine-tuned exogenous attention at the foveal scale

Exogenous attention is a rapid, involuntary mechanism that automatically reallocates processing resources toward salient stimuli. It enhances visual sensitivity in the vicinity of the salient stimulus ...
eLife

Cardenolide toxin diversity impacts monarch butterfly growth and sequestration

This important study shows that different forms and mixtures of cardenolide toxins in tropical milkweed, especially nitrogen- and sulfur-containing types, change how monarch caterpillars eat, grow, ...
eLife

Persistent contacts between Climp63 and microtubules cause mitotic defects and nuclear fragmentation

This important study reveals that mitotic release of an ER-microtubule tether is critical for normal mitotic progression. Manipulating CLIMP63 phosphorylation, the authors provide convincing evidence ...
eLife

Learning-Associated Flexibility of Cortical Taste Coding Is Impaired in Shank3 Knockout Mice

This valuable study provides solid evidence for deficits in aversive taste learning and taste coding in a mouse model of autism spectrum disorders. Specifically, the authors found that Shank3 knockout ...